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Every 10% reduction in body weight significantly decreases GERD symptoms and may even eliminate the need for acid-suppressing medication

Dual targeting of IGF-1R and PDGFR inhibits proliferation in high-grade gliomas cells and induces radiosensitivity in JNK-1 expressing cells

1 An energy-restricted diet combined with aerobic exercise is the most efficacious treatment to achieve significant and sustained weight loss, but is difficult to adhere to

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Higher doses (812 mg weekly) achieved both strong weight reduction and meaningful improvements in HbA1c, fasting glucose, and cardiovascular risk factors