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Preclinical and observational evidence, as well as some small studies, suggested potential benefits of GLP-1 agonists, but this large trial does not confirm clinical efficacy in early Alzheimers. Have the authors taken confounding factors into account
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Any change in vision, severe abdominal pain, dehydration symptoms, or possible allergic reaction should be addressed promptly
At controlled room temperature (68-77 degrees Fahrenheit), one week of exposure is well within the stability window of most compounded semaglutide formulations
The escalation proceeds through these doses with the 25mg tablet as the target maintenance dose
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