In summary, cannabis administration, via oral, smoked, and vaporized routes, modulated blood concentrations of some appetitive and metabolic hormones in cannabis users
Prescriptions of GLP-1 drugs skyrocketed by 350% between 2019 and 2024, driven mainly by prescriptions for semaglutide and tirzepatide
In vivo, reduced GRK2 levels potentiate insulin release, particularly from the RRP of insulin granules, in response to the GLP-1R agonist Exendin-4
Alcohol must reach the brain and cross the blood-brain barrier to have its effect, so the slower alcohol enters the blood, the slower it reaches the brain, says study coauthor Alex DiFeliceantonio, PhD, interim co-director of the Fralin Biomedical Research Institutes Center for Health Behaviors Research at Virginia Tech in Blacksburg
Despite reduced appetite, patients should aim to consume regular, balanced meals containing: Adequate protein (lean meats, fish, eggs, legumes, dairy) to support muscle mass and energy metabolism Complex carbohydrates (whole grains, vegetables, fruits) for sustained energy release Healthy fats (nuts, seeds, olive oil, avocado) for satiety and nutrient absorption Micronutrients from a varied diet, particularly foods containing B vitamins, iron, and vitamin D, which are essential for energy production Small, frequent meals may be better tolerated than large portions, helping to manage nausea whilst ensuring sufficient caloric intake
