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362 In addition to its role in energy metabolism, FAO contributes to CSC survival by generating NADPH, a key factor in redox homeostasis

Regulation of ferroptosis can be achieved generally by interfering with iron metabolism and ROS metabolism, and the ferroptosis process can be suppressed by iron chelators, lipophilic antioxidants, lipid peroxidation, and the depletion of polyunsaturated fatty acids and correlates with the accumulation of lipid-peroxidation markers (Stockwell et al., 2017)

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Many traditional L-glutathione supplements break down before effective absorption