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Cell Rep 32:107987 Michalski A, Damoc E, Hauschild JP, Lange O, Wieghaus A, Makarov A, Nagaraj N, Cox J, Mann M, Horning S (2011) Mass spectrometry-based proteomics using Q Exactive, a high-performance benchtop quadrupole Orbitrap mass spectrometer

Both are engineered modifications of the native sequence designed to overcome specific limitations of standard IGF-1 particularly its rapid sequestration by insulin-like growth factor binding proteins (IGFBPs)

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