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Increased ventricular wall thickness, chamber enlargement, enhanced stroke volume, and augmented diastolic filling represent adaptive responses to sustained training load and are generally associated with preserved or even supranormal functional reserve

Gutierrez GEJ, et al

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PLoS One 19(8) Shaefer CF Jr., Kushner P, Aguilar R (2015) Users guide to mechanism of action and clinical use of GLP-1 receptor agonists

Food and Drug Administration (FDA) and provided in the leaflet of the original product