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To evaluate Dihexas ability to cross the BBB and accumulate in brain regions, rats were fitted with carotid cannulas and infused with a mixture of [H]Dihexa (10 Ci) and [C]inulin (2 Ci), a vascular space marker, in 100 l of isotonic saline

Of dit ook bij mensen werkt, en via welk mechanisme, is de centrale open vraag in het onderzoek

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Retatrutide half-life comparison with other GLP-1 agonists The comparison reveals that all three major GLP-1 receptor agonists have remarkably similar pharmacokinetic profiles despite their structural differences