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Mol Neurobiol 62 , 1545015477 (2025)

MB: Writing original draft, Writing review & editing

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Notably, in addition to subcutaneous injections, the first oral Lp(a)-reducing small molecule, Muvalaplin, has also recently achieved a breakthrough, with a Phase I clinical study demonstrating that daily oral doses of Muvalaplin over a 14-day period reduced blood Lp(a) levels by up to 65 per cent [238]