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Importantly, these findings were later corroborated by in vivo studies where both acute (single high-dose striatal injection) and sub-chronic (21 days of 30 mg/kg intranasal Mn) exposure reduced GLAST/GLT-1 expression and were associated with motor deficits, at doses approximating human Mn exposure (Johnson et al., 2018

doi: 10.1097/PAS.0000000000000398 79 HaywardNKWilmottJSWaddellNJohanssonPAFieldMANonesKet al

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Cpsula: agente de recubrimiento: hidroxipropilmetilcelulosa (E-464)]