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In addition to improving insulin resistance, metformin can also alleviate cellular autophagy via regulating the PI3K/AKT/mTOR pathway to improve ovarian function
10.4254/wjh.v12.i5.184 66 KonosicS.PetricevicM.IvancanV.KonosicL.GoluzaE.KrtalicB.et al (2019)
The drugs used in T2DM were systematically compared by Alan Maloney et al 9 (data updated on the website: ): 15mg tirzepatide lowered HbA1c by 22.8 mmol/mol and weight by 10kg in patients, which were the best data ever
Riley C, Roy B, Herrin J, Spatz ES, Arora A, Kell KP, Rula EY, Krumholz HM