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The discovery of COX isozymes led to the development of selective COX-2 inhibitors, the first one being celecoxib

Drinking plenty of fluids (water, infusions, broths) facilitates intestinal transit and prevents constipation

(Talk to a health professional before making any major changes to your diet, such as removing carbs.) Clarkson read a book about lectins and cut them out of her diet which meant no legumes, beans, whole grains, dairy and certain veggies