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In this study, people took it once a day with no food or water restrictions

It was reported that in humans, after the per os administration of carnitine at doses of 30100 mg/kg, carnitines peak plasma concentrations were 2791 M after 3 h, and the carnitine concentrations returned to basal levels by 24 h

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Any use with additional weightloss medications requires close medical supervision, as noted in this guide to choosing GLP1 weightloss therapies.