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These findings have generated interest in the potential therapeutic applications of incretin-based therapies for conditions such as Alzheimer's disease, Parkinson's disease, and stroke recovery

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Collectively, the progression from exenatide to tirzepatide illustrates how extending the half-life of GLP-1R agents and incorporating additional mechanisms of action has led to substantial improvements in both glycemic control and weight loss

Cao Y, Zhang X, Shang W, Xu J, Wang X, Hu X, et al

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