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It might be the dose, the titration speed, a concurrent medication, an underlying condition, or a shift to a different GLP-1 medication entirely (tirzepatide, for instance, shows stronger average weight loss in head-to-head comparisons)

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If your aim is to sustain fat loss while reducing side effects, focus on three habits right away: protect hydration and protein intake around meals, follow a slow titration schedule that stays in place when mild symptoms appear, and keep a record of every symptom and missed dose for at least the first 12 weeks