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Experimental models show that GLP-1 receptor activation suppresses microglial overactivation and pro-inflammatory cytokine signaling, while restoring diet-induced impairments in brain-derived neurotrophic factor (BDNF) pathways [21]

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This result necessitates (i) potential reconsideration of allowable temperature ranges or allowing transient fluctuations below 1 C during RBC storage

Efimova AA, Sorokina SA, Trosheva KS, Yaroslavov AA, Shifrina ZB