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In humans, metabolism of many drugs is carried out by CYP3A, whereas in rats and dogs, CYP2C is a primary drug metabolism enzyme, as CYP3A levels in rats and dogs only reaches half the levels of their CYP2C activity

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32, 12131217 10.1124/dmd.104.001180 [DOI] [PubMed] [Google Scholar] Hysek C

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