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Elevated blood sugar directly damages the endothelial lining through a process called glycation, where sugar molecules bind to proteins and lipids, forming advanced glycation end-products (AGEs)

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Effects of Tesamorelin (TH9507), a growth hormone-releasing factor analog, in human immunodeficiency virus-infected patients with excess abdominal fat: a pooled analysis of two multicenter, double-blind placebo-controlled phase 3 trials with safety extension data