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This tripeptide has a strong affinity for copper(II) ions, and the copper complex is essential for many of its biological activities

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Kuchay MS, Krishan S, Mishra SK et al (2020) Effect of dulaglutide on liver fat in patients with type 2 diabetes and NAFLD: randomised controlled trial (D-LIFT trial)

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Whilst neurobiological mechanisms suggest plausible pathways through which these medicines might influence appetite and reward processing, definitive evidence remains limited