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Metformin offers proven cardiovascular benefits, weight neutrality or modest weight loss, and an excellent safety profile

Watch for these vital warning signs: Abnormal breathing patterns, including shallow respirations, irregular intervals between breaths, or periods of complete breathing cessation Central nervous system depression symptoms like extreme drowsiness, confusion, or inability to maintain consciousness Cyanosis (bluish discoloration) of lips, fingertips, or skin, indicating inadequate oxygenation Early recognition of these signs is imperative, as mortality rates increase drastically with delayed intervention

Gastrointest Endosc 69(1):170-2, 2009

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The development of novel GLP-1 receptor agonists, combination therapies, longer-acting formulations, and oral delivery systems are expected to further transform the market