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In an interview last year, Custer admitted how easily GLP-1s can be sort of de-blinded. He implied that asking patients to sign up for a 72-week experience where they might be randomized to a placebo could, in some cases, be gambling with their health

Stand slowly when rising from sitting or lying down, and avoid rapid position changes that trigger vertigo

Clinics that lead with clear guardrails and conservative positioning are seeing better patient confidence than those riding hype, especially as platforms and regulators start paying closer attention.

De Felice FG, Ferreira ST

Treatment decisions are individualized based on medical history, lab review, and provider evaluation