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To date, available clinical experience primarily derived from populations with T2DM or obesity receiving concomitant immunomodulatory therapies has not revealed major safety signals related to increased infection risk or immune suppression

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People are sharing stories of unexpectedly losing interest in or stopping behaviours such as: Compulsive shopping Gambling Excessive internet or app usage (just like my chess playing patient!) The Takeaway The potential for GLP-1s to influence addictive behaviours is a rapidly evolving area

It has been observed that the expression level of miR-21 in the liver of diet-induced MASH mice progressively decreased with disease progression, compared with the control group (103)