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Crucially, more clinical studies are required to definitively establish the efficacy and safety of GLP-1 RAs for the treatment of ALD and MetALD

Managing side effects : Common adverse effects of Wegovy include: Nausea, vomiting, and diarrhoea (usually transient and improving over time) Constipation Abdominal discomfort Fatigue Some of these symptoms overlap with hypothyroidism symptoms, which can make it challenging to distinguish between inadequate thyroid replacement and medication side effects

$401 million in revenue in 2025, a 16.2% net profit margin, and a total profit somewhere in the $7080 million range

That means people can take one of these drugs before anything like heart attack or stroke happens (primary), or after heart attack and stroke that could prevent another from happening (secondary)

doi: 10.1210/jc.2009-0614 90 MittempergherFPataGCreaNDi BettaEVilardiAChiesaDet al