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We will finish the review with a perspective on integrative approaches combining solid-state NMR, electron paramagnetic resonance and cryo-electron microscopy, which can complement and extend our toolkit to structurally explore various facets of prion biology

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Using LC-MS metabolomics, we found that L-cystine starvation prevented the accumulation of L-cystine and L-cysteine that normally occurs upon glucose deprivation in sensitive T98 cells (Fig

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