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Chondrocyte nonresponsiveness to insulin-like growth factor 1 in experimental arthritis

The acute spike during exercise is temporary and followed by enhanced GLP-1 sensitivity in the post-exercise period

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For example, patients with systemic primary carnitine deficiency (SPCD) have a deficiency in carnitine due to a mutation in the plasma membrane sodium-dependent high affinity carnitine transporter (OCTN2) that enables cellular carnitine uptake in the heart, muscle, and kidney