The authors also state that surgery should only be a consideration in cases where the melanosis coli occurs alongside a serious malignancy
This work was funded by the Wellcome (095101 [ALG], 200837 [ALG], 098381 [MIM], 106130 [ALG, MIM], 203141 (ALG, MIM], 203141 [MIM]), Medical Research Council (MR/L020149/1) [MIM, ALG, FK, ATH], European Union Horizon 2020 Programme (T2D Systems) [ALG, TH], and NIH (U01-DK105535
Scientific Classification A small-molecule quinolinium derivative and selective nicotinamide N-methyltransferase (NNMT) inhibitor
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A total volume of 1 mL from this pooled sample was transferred to a glass vial, evaporated using a SpeedVac concentrator, and then re-suspended in 100 L of hydrolysis solution (6 M HCl)