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Effect of laparoscopic sleeve gastrectomy vs Roux-en-Y gastric bypass on weight loss, comorbidities, and reflux at 10 years in adult patients with obesity: the SLEEVEPASS randomized clinical trial
Harmony Outcomes: A randomized, double-blind, placebo-controlled trial of the effect of albiglutide on major cardiovascular events in patients with type 2 diabetes mellitusRationale, design, and baseline characteristics
Earlier versions required strict timing and fasting conditions, which made adherence challenging
A subsequent meta-analysis involving six major cardiovascular and kidney outcome trials confirmed these early observations, showing a 36% reduction in composite kidney outcomes regardless of baseline ASCVD status [45]
