Winner KM, Chanderraj R, Nuppnau M, He Y, Petouhoff AM, Falkowski NR
Arch Toxicol 87, 155165, doi: 10.1007/s00204-012-0924-1 (2013)
A Review of the Traditional Uses, Phytochemistry and Pharmacology of Bryophyllum pinnatum (Lam.) (Crassulaceae)
Initial evaluation of whitening properties in vitro should be conducted on purified TYR and/or other melanogenic proteins, followed by the use of melanocyte cultures to examine potential cytotoxic and melanin synthetic effects
Subsequent to the data acquisition, the murine subjects were humanely euthanized via the administration of a lethal intraperitoneal injection of sodium pentobarbital, culminating in cervical dislocation