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A healthcare provider may recommend consuming more protein and engaging in resistance training to prevent sarcopenia (a loss in muscle mass)

Gene expression modulation studies (over 4,000 human genes documented)

Growth retardation and cysteine deficiency in gamma-glutamyl transpeptidase-deficient mice

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In this context, recognition of SAGE-DM may have practical implications by encouraging clinicians to consider alternative therapeutic priorities, including preservation of muscle mass, avoidance of overtreatment, correction of hormonal and nutritional imbalances, and individualized metabolic targets