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doi: 10.1096/fasebj.8.15.8001745

Published online 2017 Nov 30

Allergy and inflammation Mast cells and basophils can release histamine during allergic and inflammatory responses, contributing to itching, congestion, flushing, swelling and bronchial symptoms

FIGURE 6 Infants have low PEPCK and glycogen phosphorylase activities and high GS activity compared with adults (Figure 6)

Mechanistically, ALM activates retinoid X receptor- (RXR) through stable hydrogen bond formation, thereby upregulating caudal-type homeobox transcription factor 2 (CDX2) and cystic fibrosis transmembrane conductance regulator (CFTR), while concurrently suppressing -catenin/Snail-mediated epithelial-mesenchymal transition (EMT)