doi: 10.1016/j.tins.2016.01.003 219 HurJ-Y
Ali said the updated guidance should not scare users and that the decision took patient safety into account
Given this situation it is particularly concerning that MDA campaigns show that PZQ cure rates are often less than 50% and modeling studies demonstrating that these campaigns with PZQ alone are unlikely to interrupt transmission, and once MDA is suspended, the prevalence of infection is likely to rebound to pre-MDA levels 9,10,11
Retinoids regulate stem cell differentiation
Longer-term concerns include potential nutrient deficiencies (particularly fibre, certain vitamins, and minerals), increased LDL cholesterol in some individuals, and the restrictive nature of the diet, which many find difficult to maintain