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Cardiologists will need to counsel patients through that and acclimate them to giving these drugs by subcutaneous injection. Meanwhile, he adds, future research is needed to address whether semaglutide exerts the same protective effects for primary prevention of cardiovascular disease in high-risk individuals with overweight or obesity

For a substance to pass through the skin and into the bloodstream in meaningful amounts, its molecules typically need to be very small (under 500 Daltons)

We need to move away from binary decisions about medication access toward an individualized approach to treatment selection and support.