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Estrogens lead to an obvious increase in hepatic tumor necrosis factor (TNF)- and hepatic myeloperoxidase (MPO) levels in the liver tissues by 346 and 232%, respectively (Wadie et al., 2021)

iGL cells were exposed to different mediums: iGL cells culture medium (Cell only), iGL culture medium supplemented with synthetic Exe4 peptide (Exe4 solution) and with scExe4 peptide secreted from Hepa1-6 and HeG2 cells transfected with the scExe4 expression plasmid (scExe4_Hepa1-6 and scExe4_HepG2, respectively)

In Phase II, the liver attaches a glutathione molecule to the toxin (a process called conjugation)

Vitamins like B12, iron, and zinc help promote melanin production, which may enhance therapy results