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HbA1c for the repaglinide-treated groups (1 and 4 mg groups combined) at the end of the study was decreased compared to the placebo-treated group in treatment nave patients and in patients previously treated with oral hypoglycemic agents by 2.1% and 1.7%, respectively
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17 Conversely, findings from another population-based study suggested there was no overall increased risk of DR associated with GLP-1RA use, while a meta-analysis indicated albiglutide, a GLP-1RA no longer commercially available due to limited prescribing, was associated with an increased risk of early worsening (the four GLP-1RAs available did not exhibit a statistically significant association with DR)
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