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In the body, it regulates metabolism in the epiphysis, increases the sensitivity of the hypothalamus to its natural hormonal influences, and normalizes the function of the anterior pituitary, including its regulation of gonadotropins and melatonin
This direct administration into muscle or subcutaneous tissue allows for substantially higher bioavailability, meaning a greater percentage of administered glutathione reaches systemic circulation in its intact, active form
Depletion of intracellular GSH in HepG2 cells with BSO treatment was without effect on cell viability as assessed by MTT assay (Fig