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The antibiotic-potentiating ability of ciprofloxacin against various organisms has been demonstrated by various scientists, most of whom targeted the efflux pumps
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Though a few studies provided implications that SARS-CoV-2 could accelerate its entrance into the infected cells by leveraging up-regulation of its receptor gene ACE2 via induction of cytokine storm involving IFNG, TNF- as well as NFK (50, 51), physiologically ACE2 still has a significant anti-inflammatory role
