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Interestingly, Bottari and colleagues reported even higher circulating markers of oxidation (MDA and AOPP) after CHOP chemotherapy (cyclophosphamide, vincristine, doxorubicin, and prednisone) in dogs with multicentric lymphoma, suggesting that the treatment might exacerbate OS levels [74]

15,16 Even with the addition of SGLT-2 inhibitor therapy, the residual risk of kidney function decline remains high (at 2 to 3 mL/min/1.73 m 2 per year) in people with severely increased albuminuria

These medications are contraindicated in patients with a personal or family history of medullary thyroid carcinoma or Multiple Endocrine Neoplasia syndrome type 2

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