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According to the existing literature, it is found that the main active components of the three types of BC are bile acids, bile pigments, Tau, amino acids, and a variety of trace elements

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Cycle changes are usually most marked during the first 3-6 months of treatment, then stabilize as weight loss plateaus

Read together with the failed fosgonimeton trial, the takeaway is that the human-relevant evidence base for this class is both thin and, where it touched humans, negative