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We set the national incidence of the primary MACE endpoint over 54 months equal to that observed in the placebo arm of the SOUL trial (668 events among 4,825 participants, or 13.844%)

Telogen effluvium, the likely underlying cause, is generally self-limiting and affects a proportion of individuals undergoing rapid weight reduction, regardless of the method (whether pharmacological, surgical, or dietary)

Take 1 capsule 1 to 3 times daily, preferably with food

The filtrate then enters the loop of Henle, first at the descending limb and then the ascending limb

Results showed progressive decreases in HbA1c values at 30, 60, and 90 days