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Sonthalia, S.,et al (2016) Vitamin C -Ascorbic Acid (vitamin C, AsA), is the most plentiful antioxidant in human skin The idea behind using antioxidants for skin-lightening activities lies in the hypothesis that the oxidative effect of UV-irradiation contributes to activation of melanogenesis As it interferes with melanin synthesis -reducing oxidized dopaquinone -interrupting DHICA oxidation -preventing action of tyrosinase Int J Mol Sci

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Glutathione Is a Key Player in Metal-Induced Oxidative Stress Defenses Kwon D.H., et al