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In a mouse model of AD, activation of Wnt signaling has been shown to reduce amyloidosis by decreasing APP cleavage and A formation (Pschl et al., 2013)

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More than 3,000 product liability lawsuits are pending, largely focused on gastroparesis and vision injuries such as non-arteritic anterior ischemic optic neuropathy (NAION), now centralized in two MDLs in the Eastern District of Pennsylvania before Judge Karen Marston