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Nutrients, 13 (9), 2917

The growth of prostate cancer cells depends on the continuous activation of androgens, the androgen receptor (AR) and its splice variants, which remain the main driver of CRPC progression

As a consequence of AKI, a significant number of oxygen free radicals are produced, endogenous antioxidants are continually depleted, and high levels of inflammatory substances are secreted, all of which contribute to kidney damage progression (Han and Lee, 2019)

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