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Data availability Data used in these analyses are available on Open Science Framework ([ (https:/osf.io/r2whq)), with age provided in bands to preserve participant anonymity

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When Semaglutide Is Clearly Superior For the majority of weight loss patients, semaglutide is the superior choice: Significant weight loss needed (30+ lbs): Contrave's 58% weight loss is insufficient for patients with BMI 35+