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16 17 18 Newly emerging indications for GLP-1 medicationsincluding heart disease, metabolic liver disease, peripheral artery disease, Alzheimers/dementia risk, and even alcohol and substance use disorders, as highlighted in a 2025 study in JAMA 19 suggest these drugs may soon play a much broader role in medicine than just treating diabetes or obesity

Glucose levels in blood after intestinal administration of semaglutide exceed those achieved after intravenous administration (Figure 6)

While it doesnt provide energy itself, it plays an essential role in transforming nutrients into usable energy Impact on Fatigue : If youre significantly deficient in vitamin B12, taking a supplement or increasing your intake will likely improve your energy level

So investors have to take the update with a grain of salt

10.1016/j.iac.2009.02.007 25 GuanK