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On its own, this observation does not distinguish whether GPI linkage potentiates activity by fostering membrane association per se or by preventing diffusion of the ligand, which would reduce its local concentration

Through single-bacteria stable isotope tracing analysis and computational simulations, the study further elucidated that Bacteroides synthesizes polyamines via specific metabolic pathways, underscoring the critical role of the intestinal microbiota in polyamine metabolism (113)

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Nutrient Agar: 1000 mL of distilled water was mixed with 3 g of beef extract, 10 g of peptone, 5 g of sodium chloride, and 15 g of agar

doi:10.1016/j.biomaterials.2025.122256