It has been studied in preclinical models, cell cultures, and animal research for effects across a broader range of tissue types than most peptides of comparable size, including angiogenesis, nitric oxide signaling, and tendon, ligament, and muscle healing models
However, a more localized synaptic expression of MET in the adult brain was indeed shown (Eagleson et al., 2013)
Journal of Leukocyte Biology
Product quality, formulation, and concentration all affect how much active compound actually penetrates to produce benefits
Cancer Res 66 : 17211729 Chan PC, Liang CC, Yu KC, Chang MC, Ho WL, Chen BH, Chen HC (2002) Synergistic effect of focal adhesion kinase overexpression and hepatocyte growth factor stimulation on cell transformation