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55,58,59 Therefore, NNMT and CYP2E1 divert NAM from recycling to NAD + , restraining NAM accumulation and inhibition of NAD + -dependent signaling

Biotin and B- complex are also common add-ons depending on your goals

Options may include phentermine-topiramate, a combination medication that suppresses appetite, as well as medications originally approved for other conditions, such as the antidepressant bupropion (Wellbutrin) or the diabetes drug metformin

Most cases resolve within 4-8 weeks as the body adjusts to the medication

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