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Description

Thus, at least in the advanced stages of atherosclerosis, lysosome dysfunction contributes to the overall lesion severity

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doi: 10.1016/j.msec.2018.04.048 247 ShahverdiARShahverdiFFaghfuriEReza KhoshayandMMavandadnejadFYazdiMHet al

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While GLP-1 and GIP receptor activation primarily reduce energy intake through appetite suppression and delayed gastric emptying, glucagon receptor activation continues to drive energy expenditure through thermogenesis and hepatic fat oxidation regardless of whether caloric intake has already decreased

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