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4b), including peaks at 3424 cm 1 (overlapping of OH and NH stretches), 2925 cm 1 (asymmetric CH 2 stretching vibration from the pyranose ring), 1648 cm 1 (C = O asymmetric stretching), 1549 cm 1 (NH 2 groups), 1382 cm 1 (C-H bending), 1321 cm 1 (NH wag of primary and secondary amine), 1155 cm 1 (COC linkage), 1074 cm 1 (P = O stretching), 896 cm 1 (antisymmetric stretching vibration of COC bridges assigned to the glucopyranose ring in the CS matrix), and 529 cm 1 (OH out-of-plane bending vibration)

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Interindividual variability further complicates research, as aging and sleep patterns differ widely among individuals, making it difficult to generalize findings and establish universal mechanisms

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The research rationale for combining the two peptides rests on their convergent yet mechanistically separate modes of action

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Phytother Res 20(12):11031105 Panda S, Kar A (2007) Annona squamosa seed extract in the regulation of hyperthyroidism and lipid-peroxidation in mice: possible involvement of quercetin

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