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What they probably didnt mention is that functional B12 deficiency can begin at levels well above the standard cutoff and that by the time serum B12 drops below the labs flagged range, neurological damage may already be underway

Nature 586 , 567571 (2020)

The association of RPS3 with glutathionylated LcrV suppresses apoptotic cell death and triggers the release of inflammatory cytokines IL-1 and IL-18

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Another potential interaction is with oral medications