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Patients should inform their anaesthetist if: They have continued taking GLP-1 medication closer to surgery than recommended They experience symptoms such as nausea, bloating, or feeling unusually full They have any concerns about their medication management By following the individualised advice from your anaesthetic and surgical team, the risk of complications can be substantially reduced whilst maintaining the important metabolic benefits these medications provide in the longer term

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Gastrointestinal Effects Nausea affects approximately 28-31% of women at the 12mg dose, with higher rates during dose escalation periods

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Glutathione synthesis In the cell, glutathione de novo synthesis occurs in the cytosol before being pumped into mitochondria [2]